Acta Virologica Vol.61, No.2, p.223-225, 2017

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Acta Virologica Vol.61, No.2, p.223-225, 2017
Title: Inactivation of tobacco mosaic virus using gamma irradiation and its potential modes of action
Author: R.-D. JEONG, H.-S. CHOI

Abstract: Gamma irradiation is a non-thermal processing technique used to disinfect harmful microorganisms in agriculture. This technology has been shown to be an effective method to control bacterial and fungal plant pathogens. However, its effect on viral plant pathogen is less understood. Gamma irradiation was evaluated for the inactivation of tobacco mosaic virus (TMV). TMV infectivity has gradually decreased following irradiation in a dose-dependent manner and virus was completely inactivated at a dose over 40 kGy. Transmission electron microscopy revealed that increased gamma irradiation disrupts the virion structure and degrades viral proteins, which results in TMV inactivation. The mechanisms, through which gamma irradiation inactivates TMV, can be directly associated with the damage to the virus constituents.

Keywords: coat protein; gamma irradiation; inactivation; tobacco mosaic virus; virion
	Published online: 19-May-2017
Year: 2017, Volume: 61, Issue: 2	Page From: 223, Page To: 225
doi:10.4149/av_2017_02_14
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