Home Bratislava Medical Journal 2021 Bratislava Medical Journal Vol.122, No.4, p.251–255,2021

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.2


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Bratislava Medical Journal Vol.122, No.4, p.251–255,2021

Title: Neutrophil-to-lymphocyte ratios in pregnant women with familial mediterranean fever
Author: A. Keles, D. Iskender, O. Yucel Celik, G. Dagdeviren, C. Iskender, A. T. Caglar, S. Celen

Abstract: OBJECTIVE: To investigate the association between maternal serum neutrophil-to-lymphocyte ratios (NLRs) and pregnancy outcomes in women with familial mediterranean fever (FMF).
BACKGROUND: FMF exists worldwide, it primarily affects Mediterranean countries
METHODS: We retrospectively analysed data from 269 pregnant women, who underwent a routine prenatal follow-up and delivery in our hospital from 2016 to 2020. Clinical and demographic data, including age, gravida, parity, abortus, proteinuria in the first trimester, NLR, obstetrical complications, gestational age at delivery, birthweight were retrieved from the patients’ medical records. Data from 67 pregnant women with FMF and 202 healthy pregnant women were compared.
RESULTS: Patients with FMF showed higher rates of preeclampsia and primary caesarean delivery; however, there were no differences between the groups in terms of other obstetric complications or adverse neonatal outcomes. In both the FMF and control groups, NLRs in the third trimester were significantly higher than those in the first trimester. Additionally, patients in the FMF group demonstrated higher NLRs than patients in the control group in the third trimester.
CONCLUSIONS: The NLRs are a haematological parameter that can be used to predict subclinical inflammation and the effects of ongoing subclinical inflammation on the pregnancy outcomes in women with FMF (Tab. 4, Ref. 39).

Keywords: familial mediterranean fever, neutrophil-to-lymphocyte ratio, obstetrical complications, pregnancy, subclinical inflammation
Published online: 16-Mar-2021
Year: 2021, Volume: 122, Issue: 4 Page From: 251, Page To: 255

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